The Savvy Diabetic


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19th Annual Shooting Stars JDRF Walk to Cure Diabetes Sunday, October 26, 2014 in Newport Beach, CA

For a contribution of $45 (or MORE!), walkers will receive a VERY COOL Shooting Stars Team T-Shirt along with FREE pastries, bagels, and coffee or juice. Questions or to Register email If you are unable to attend but would LOVE to donate on-line go to:

T1D Exchange and their First Annual Diabetes Innovation Challenge

This is exciting!






T1D Exchange and M2D2, a joint venture of the University of Massachusetts Lowell and Worcester campuses that incubates medical device start-ups,  have announced the first annual Diabetes Innovation Challenge (2016).


The Diabetes Innovation Challenge will provide up to two awards of up to $150,000 in cash or in-kind services provided by T1D Exchange, M2D2, and Challenge sponsors, including the American Diabetes Association and JDRF.

For this year’s innovation Challenge, nearly 60 innovators submitted their applications for consideration. T1D Exchange has narrowed the list down to 26 semi-finalists.

Now, semi-finalists will pitch their innovations in one of two competitions in front of a panel of esteemed judges (think Shark Tank) with the hopes of advancing to our finals event.

Who We Selected

Semi-finalists were chosen based on a few criteria, including what stage of development their innovation was (either early stage or translational) and whether their solution fit into one of our four innovation categories (a device, diagnostic, therapeutic or technology).

Here’s a quick look at just a few semi-finalists:

from Enable Biosciences, an ultrasensitive auto-antibody test to detect diabetes sooner than what’s possible today

from CamMed, a thin, flexible patch pump for one or multiple injectable medications

from Dibatech, a portable and re-chargeable device that can keep insulin stable at unfavorable temperatures in areas with erratic power supply (focused on third-world countries)

from Sproutel, a smart teddy bear teaching tool that helps young helps children gain hands-on skills in diabetes management (through play)

from Clinitech, an electronic band-aid for noninvasive glucose monitoring

What’s next?

T1D Exchange will host two semi-finals events in late September and early October. From there, finalists will be selected who will present their solutions in late October to another panel of esteemed judges. While award winners will receive […]

Clinical Trial OPEN: Liver-Targeted Insulin More Effective than Insulin?

Trial name: Study of HDV Insulin Versus Insulin in Type 1 Diabetes Subjects

Diabetes type: Type 1 diabetes

What the trial is testing: This six-month study will test the safety and efficacy of HDV insulin, a new technology that directs meal-time rapid-acting insulin toward the liver.

What the trial is measuring: The trial will test HDV insulin’s effect on A1c, fasting blood glucose levels, frequency of low blood sugar (hypoglycemia), body weight, and insulin dose.

Why this is new/important: HDV (“Hepatocyte Directed Vesicle”) technology consists of small molecules that attach to insulin and deliver it to the liver. In people without diabetes, the liver uses up to 80% of the pancreas’ entire insulin production, storing glucose for later release to counteract low blood sugar. The liver houses the only cells in the body that can both store and release glucose; cells in other tissues can use glucose in response to pancreatic or injected insulin, but because they are not exposed to the liver’s glucose-releasing hormone, glucagon, they are unable to release stored glucose to counteract low blood sugar. In contrast, only a fraction of injected insulin reaches the liver, leaving most to act on other tissues.

Targeting insulin specifically to the liver at meal-time is an exciting improvement because it more closely mimics the body’s natural insulin production. Some believe it will bring a lower risk of hypoglycemia and less weight gain.

Safety concerns impeded the testing of an earlier version of liver-targeted insulin called peglispro. This new form of basal insulin was made by Lilly Diabetes for use in people with type 2 diabetes, but issues with liver enzymes halted development. With a different liver delivery mechanism and pre-meal instead of basal insulin, Diasome hopes its HDV technology will […]


Afrezza is BACK!  After Sanofi terminated its marketing partnership with MannKind, MannKind has relaunched its fast-acting inhalable insulin, Afrezza, as reported in on 30 August, 2016.  I, for one, couldn’t be happier and more relieved.





I have been using Afrezza for about 1-1/2 years, on an as-needed basis, when:

my bg runs and seems to stay high, despite having taken the best calculated bolus. Afrezza seems to help my bg’s come back down and then it just levels off.  It feels miraculous!
I’ve eaten a heavy-carb meal and I know that my bolus just will have difficulty keeping up with it. Afrezza seems to round off the spike and bring my bg’s back down gently. An amazing management tool for me!

Are there side effects or concerns? Yes, definitely.

Afrezza can cause an irritating little cough and feel uncomfortable on the inhale. I try to remember to sip water before inhaling and I inhale slowly.  Seems to help.
Long term warnings include breathing problems and a small risk of lung cancer.

But I don’t use it every day so I feel I have downplayed my risks.

Afrezza is an ultra-rapid-acting insulin for people with type 1 and 2 diabetes, peaking in only 16-21 minutes versus about 60-90 minutes for current injected rapid-acting insulins – that’s a big difference! It lasts two-to-three hours less than other rapid-acting insulins. This is an important advantage for a mealtime insulin – fast-in, fast-out ensures the insulin covers food quickly, without lingering and causing delayed low blood sugar.

Going forward, MannKind will sell and market the product directly, and offer added programs to make it easier to get and use.

A new Afrezza Patient Savings Card and Reimbursement Program









A new starter pack, with a 30-day titration pack combining 90 […]

By |September 25th, 2016|Extra|0 Comments

SPOTLIGHT: On The Bonnie Sher Show!

A STAR is BORN!  Yup, little ‘ol me!  Mr. deMille, I’m ready for my close-up!!!  OK, enough!

I was honored to be asked to be a T1d Co-Host on The Bonnie Sher Show, broadcast on UBN internet radio/tv, on Thursday, 15 September 2016.  Bonnie is a long-time T1 as well and it seems our paths took similar turns from our growing up days in New York.  Bonnie is a singer/actress whose career was beautifully mentored by Sammy Davis, Jr.  She is a vocal T1 advocate as well as a dog lover and a truly compassionate human being.

Here’s the link to the rebroadcast … my segment is the second half of the show.  The first half is a great interview with songwriter/producer Bob Esty, also a T2 … the big sound of Donna Summer in the disco era and he also writes for Barbara Streisand.

Enjoy and many thanks to all my T1 friends!


By |September 18th, 2016|Extra|0 Comments
  • Counter Culture Labs
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    WAY OUT THERE: Non-Scientists Try to Break Up Monopoly on Insulin

WAY OUT THERE: Non-Scientists Try to Break Up Monopoly on Insulin

OK, … this is WAY OUT THERE … or is it? (this is not a recommendation or endorsement)

Listen to this podcast from The Pulse, reporting on an Oakland, CA grassroots community lab for biohacking and citizen science.

According to their website,

“We are Counter Culture Labs, a community of scientists, tinkerers, biotech professionals, hackers, and citizen scientists who have banded together to create an open community lab — a hackerspace for DIY biology and citizen science.”


Biology is the technology of the 21st century, and has the potential to affect our lives as much as or more than computers did in the 20th century. Our goal is to demystify and democratize this technology, putting tools into the hands of those who want to learn.






Read/listen more: Counter Culture Insulin?

By |September 18th, 2016|Featured|0 Comments

Savvy Updates: 9/18/2016: Pilots Fit to Fly with Diabetes, Need More T Cells to Stop Type 1 Diabetes, Glooko and Diasend Merge, Medical-grade Wearables White Paper

Commercial airline pilots flying with insulin-controlled diabetes had no incidents of medical incapacitation in more than 18 months of study, researchers reported by the European Association for the Study of Diabetes, 12 September 2016 via

The study was conducted by the medical staff at Royal Surrey County Hospital and the U.K. Civil Aviation Authority (CAA), based at London’s Gatwick Airport.
The researchers found that at the analysis date, 26 insulin-treated pilots had been issued with Class 1 medical certificates. All were men, with an average age of 41. The majority (85%) had type 1 diabetes, with an average diabetes duration of 8 years.
Of the 26 insulin-treated pilots flying planes under the U.K. flag, a total of 8,897 blood glucose monitoring values had been recorded during 4,900 flight hours with more than 96% of the cockpit glucose monitoring readings indicating pilots with diabetes were in the “Green Zone” for safety, reported Julia Hine, MD, of the Royal Surrey County Hospital in Guildford, England. That aviation agency defines the “green zone” as glucose levels between 90 to 270 mg/dL
U.S. pilots with a diagnosis of diabetes are not permitted to pilot commercial airlines.
Read more: U.K. Airline Pilots Fit to Fly With Diabetes

Do You Need More T Cells to Stop Type 1 Diabetes? The FDA fast-tracks a treatment that would, in theory, use T cells to stop Type 1 diabetes in its tracks, as reported by Kathleen Doughty of Insulin Nation, 9 September 2016.

A novel treatmen t meant to stop Type 1 diabetes by increasing the number of T cells in the body is being given special attention by the FDA. The treatment, called CLBS03, has recently been granted Fast Track status by federal regulators, a designation which […]

By |September 18th, 2016|Featured|0 Comments
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    I’m Heading to Hollywood for T1! Tune In and Call in THURSDAY, 9/15!!!

I’m Heading to Hollywood for T1! Tune In and Call in THURSDAY, 9/15!!!

That’s right!  I’m on my way to Hollywood!  OK, well, kinda!  But I’m excited!  I’ve been invited to be a T1 Co-Host on The Bonnie Sher Show in Channel 2 of the Universal Broadcast Network (UBN).

WHEN:  Thursday, September 15, 2016, 2pm -3pm PST.
CALL-IN: 1-323-843-2826 (only during the live broadcast)

Bonnie is a long-term T1 as well as a singer/actress from a show business family.  She’s funny and bright and kind and passionate. The first half of her show is usually dedicated to someone in the show business world. The second half is focused on Bonnie and her T1 co-host.

If you can’t rearrange your life to be glued to your computer, tablet or smartphone, Bonnie posts shows on her website:

Poke around the site … it’s fun reading. Feel free to offer comments and thoughts.


If you want to see one of our fascinating GNO’ers, Roger Sparks with Bonnie


By |September 13th, 2016|Extra|0 Comments

Savvy Updates: 8/30/2016: Which Came First? Antibiotics OR Bacterium?

Antibiotics Linked to T1D in Mice, according to a study at NYU Langone Medical Center, reported in Nature Microbiology, August 22, 2016 and published in MedPageToday, Endocrinology, August 24, 2016. The study results center on the microbiome, the bacterial species in our guts that co-evolved with humans to play roles in digestion, metabolism, and immunity. As children’s exposure to microbe-killing antibiotics has increased in recent decades, the incidence of autoimmune diseases like type 1 diabetes has more than doubled. The average American child currently receives 10 courses of antibiotics by age 10.

Specifically, the new study found that short pulses of antibiotics cause mice that are susceptible to type 1 diabetes to develop the disease more quickly and more often than mice not treated with antibiotics.

“Our study begins to clarify the mechanisms by which antibiotic-driven changes in gut microbiomes may increase risk for type 1 diabetes,” says Martin Blaser, MD, The Muriel G. and George W. Singer Professor of Translational Medicine at NYU School of Medicine and the study’s senior author. “This work uses NOD mice, the best model of type 1 diabetes to date, and doses of antibiotics like those received by most children to treat common infections.”


‘This latest study result is compelling, linking the effects of use of antibiotics in mice to type 1 diabetes,” says Jessica Dunne, director of Discovery Research at JDRF who funded this research. “This is the first study of its kind suggesting that antibiotic use can alter the microbiota and have lasting effects on immunological and metabolic development, resulting in autoimmunity.”


Read more:  Antibiotics Linked to T1D in Mice

Want more about the effects of antibiotics?

Antibiotics Weaken Alzheimer’s Disease Progression Through Changes in the Gut Microbiome
Antibiotic Use Linked to Type […]

Fit2Me by AstraZeneca – Customize Your Lifestyle/Fitness/Recipes






Check out AstraZeneca’s new website,, designed to help those with diabetes succeed in living a healthful life.  It’s an interesting concept, very user-friendly, which allows you to very specifically choose foods and cuisines that you love, types of activities you love and treatment plans that help you interact well with your healthcare professionals.  You choose a Fit2Me coach from a list of 6 coaches (all with different “personalities” and styles of managing) who then guides you through choices and decisions.

I experimented in the Activities module, which allowed me to opt for the types of activity I prefer and then helped me to build my schedule to include those options.  You are encouraged and spurred on by your “coach” to stick to the program … and you also can accumulate points for your successes.

Under the Food module, I was able to indicate the cuisines that I prefer, how much cooking I’m willing to do, list my favorite foods and identify foods I avoid.  Then, when I choose the kind of meal I’m looking for (such as dinner or snack, etc.), it displays images with dishes, along with nutrition values and preparation information.  I can see that this would absolutely help me on those days when I just can’t figure out what I want and should eat.

I can track my points, which earn me entry into Sweepstakes, from which I can choose prizes (such as pedometer, exercise mat, alarm clock pill box, microwave steamer, etc.), enter and display my “winning” streak of successes and victories.

The only thing that is missing, for me, is the ability to choose Type 1 diabetes under my health challenges, as it is primarily .  But in all reality, this […]

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